Cobb Syndrome





Cobb syndrome (Cutaneomeningospinal angiomatosis) consists of a capillary malformation that has a high-flow nature on the posterior thorax in association with a spinal involvement (AVM of the spine). Sometimes the vertebral bodies are involved. Neurological problems commonly arise due to cord compression or spinal hemorrhage. The spinal AVMs are most commonly intramedullary, but may be meningeal or perimedullary.   

MRI and/or conventional spinal arteriogram demonstrate a high flow vascular anomaly.

On rare occasions, the posterior AVM may be seen like a port-wine stain (“pseudo-port-wine stain”).



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